Website: Borschel Lab
Department: U of T Division of Plastic & Reconstructive Surgery
Research Interests:
Our group seeks to elucidate novel mechanisms by which peripheral nerves regenerate following injury. We are developing unique biomaterials and growth factor based methods to improve nerve regeneration, and through the use of bioengineering, small molecules and cell based treatments, we strive to enhance outcomes following nerve injury.
Recent Stem Cell Publications:
Whitlock EL, Tuffaha SH, Luciano JP, Yan Y, Hunter DA, Magill CK, Moore AM, Tong AY, Mackinnon SE, Borschel GH Processed allografts and type I collagen conduits for repair of peripheral nerve gaps. Muscle Nerve. 2009 Jun;39(6):787-99.
Moore AM, Borschel GH, Santosa KA, Flagg ER, Tong AY, Kasukurthi R, Newton P, Yan Y, Hunter DA, Johnson PJ, Mackinnon SE. A transgenic rat expressing green fluorescent protein (GFP) in peripheral nerves provides a new hindlimb model for the study of nerve injury and regeneration. J Neurosci Methods. 2012 Feb 15;204(1):19-27.
Moore AM, Wood MD, Chenard K, Hunter DA, Mackinnon SE, Sakiyama-Elbert SE, Borschel GH. Controlled delivery of glial cell line-derived neurotrophic factor enhances motor nerve regeneration. J Hand Surg Am. 2010 Dec;35(12):2008-17.
